RAF Typhoon FGR4s have operated alongside France's air force in a combined operation against an subterranean weapons facility in Syria employed by the Daesh militant organization, per a report from the British defence ministry.
The location, identified by intelligence, was assessed as containing munitions and bombs, the statement said, and was positioned in mountainous terrain just to the north of Palmyra in Syria's central region.
"The RAF jets used precision-guided Paveway IV munitions to strike a several access tunnels providing entry to the site... early reports indicate the strike was effective," the ministry announced.
There was no indication of any harm to civilians in the operation on Saturday evening and each participating jet returned to base without incident, the MoD added.
The Typhoon FGR4s were backed up by a Voyager tanker plane.
The Islamic State group - alternatively referred to as Daesh - imposed militant control over significant areas in Iraq and Syria before its territorial defeat in 2019.
"This operation underscores British leadership, and determination to operate in unison with our partners, to stamp out any resurgence of the terrorist group and their violent and radical beliefs in the area," Britain's Defence Chief the Defence Secretary said.
UK warplanes have performed patrols over Syrian airspace to "deter any attempted resurgence" of the group subsequent to its routing at the climactic battle in Baghuz in 2019, the authorities noted.
"I want to thank all the members of the UK armed forces involved in this operation for their skill and their courage," the Defence Secretary added. "They were part of a great many British troops on duty over Christmas and New Year. This mission, to remove militants who threaten our safety, highlights how UK forces are always on standby, continuously, keeping Britain secure at home and strong abroad."
In December, the US military conducted what it termed a "major assault" on Daesh sites in Syria, subsequent to an attack claimed the lives of two US servicemembers and a local interpreter in the Palmyra area.
The UN says Daesh still has roughly 5-7 thousand combatants in Iraq and Syria.